ASXL1/2 MUTATIONS AND MYELOID MALIGNANCIES

ASXL1/2 mutations and myeloid malignancies

Abstract Myeloid malignancies develop through the accumulation of genetic and epigenetic alterations that dysregulate hematopoietic stem cell (HSC) self-renewal, stimulate HSC proliferation and result in differentiation defects.The polycomb group (PcG) and trithorax group (TrxG) of epigenetic regulators act antagonistically to regulate the expressi

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Phenotype-genotype correlations among carbapenem-resistant Enterobacterales recovered from four Egyptian hospitals with the report of SPM carbapenemase

Abstract Background Carbapenem-resistant Enterobacterales (CRE), currently listed by the World Health Organization (WHO) as top priority critical pathogens, are a major global menace to human health.In low- and middle-income countries (LMICs) the threat is Plush Toys mounting fueled by selective pressures caused by antibiotic abuse and inadequate d

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Cloud platform functionality in visual media

The rapid Face Serum changes in the field of transferring and exchanging information via cloud platforms have revolutionized the field of modern visual media, as cloud computing technology has greatly influenced the media institutions, providing effort, money and high-quality materials.The research included five chapters, the first came under the m

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